The challenge for many is in keeping the pace of database infrastructure (SAP HANA) in sync with that of innovations that are being delivered by SAP for SAP S/4HANA ERP. Infrastructure is expensive, especially DRAM, which is crucial for processing of high-volume data at high speed and in-memory. Intel Optane on Lenovo ThinkSystem portfolio presents a new revolution in memory persistency with SAP HANA . That means, SAP HANA detects the persistent memory which in this case is Intel Optane and adjusts itself by placing the right data structures on persistent memory and leaving the others in DRAM. With Intel Optane memory on Lenovo ThinkSystem portfolio, an end user can achieve lowest TCO with greater performance. In this workshop we will look at why this is crucial for system performance. We will also explore some relevant business cases including Intel Optane as a persistent memory on Lenovo ThinkSystems in the hardware landscape for an organization running on SAP S/4HANA.